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DNA binding of complexes 1a, 1b, 2a, 2b, and cisplatin with double-helical calf thymus DNA (c(Pt)/c(DNA nucleotides) = 0.02) in 10 mM NaClO4 at 37°C. Stars at the top of the bars indicate a statistically significant difference from cisplatin (∗p ≤ 0.05, ∗∗p ≤ 0.01). Data represent a mean ± SEM of two independent experiments, each measured in triplicate.
