Figure S1.

Illustration of mutations on spike of Omicron variant and epitopes for RBD-targeting antibodies, related to Figure 1

(A) The mutations in Omicron variant are shown on spike. The monomeric spike is shown as gray cartoon. The mutations are depicted as spheres in indicated colors. (B) Epitopes for ACE2 and three classes of RBD-targeting antibodies. The residues involved in interaction with antibodies were calculated by ePISA (Proteins, Interfaces, Structures, and Assemblies) and COOT (Crystallographic Object-Oriented Toolkit) and are depicted in colored squares.