Figure 1. The ophthalmoscopic examination, ultrasonography, SD-OCT, fluorescein angiography, indocyanine green angiography, MRI and hematoxylin and eosin (HE) staining of Case 1.

A: Ophthalmoscopy demonstrated a large posterior retinal detachment overlying an amelanotic mass (7 to 8 times the papillary diameter) in her right eye. B: On ultrasonography, the mass showed relatively low to medium reflectivity with a homogeneous internal structure and was measured 12.8 mm in width and 8.1 mm in height. C: SD-OCT showed a hyperreflective band associated with intra-subretinal fluid and hairy photoreceptors. D: Fluorescein angiography (FFA) showed a big uveal space occupying lesion with hypo-fluorescence at the superior temporal margin of the optic disc. Progressive choroidal hyper-fluorescence small-caliber vessels were seen in the initial phase without retinal-choroidal anastomosis and staining of the tumor and fluorescein leakage were observed in the late phase. E: Indocyanine green angiography (ICGA) also revealed the choroidal mass, intrinsic choroidal vasculature (double circulation) in the early phase and massive fluorescein leakage in the late phase were also observed. F: MRI showed that uveal schwannoma was hyperintense on T1WI spin-echo (SE) images and hypointense on fast SE (FSE) T2-weighted images (T2WI) with respect to the vitreous body in all 3 patients. Nevertheless, uveal schwannoma showed isointensity on T1WI SE and FSE T2WI images with respect to the brain. G: HE staining demonstrated that the tumor was composed of spindle-shaped cells which were densely arranged in bundles with abundant cytoplasm and round nucleus.