Table 4.

CRS and ICANS all and according to G-CSF administration.

	All		Early G-CSF		Control		p
	n	%	n	%	n	%
Any grade n (%)	89	73%	24	72.7%	65	73%	1
CRS gr 1 n (%)	51	41.8%	10	30.3%	38	42.7%	0.21
CRS gr 2 n (%)	40	32.8%	13	39.4%	27	30.3%	0.34
CRS gr ≥3 n (%)	1	0.8%	1	3%	0	0%	–
Any grade n (%)	32	26%	9	27%	23	25%	0.37
ICANS gr 1 n (%)	16	13%	3	9.1%	13	14.6%	0.42
ICANS gr 2 n (%)	11	9%	5	15.2%	6	6.8%	0.15
ICANS gr ≥3 n (%)	5	4%	1	3.03%	4	4%	0.71
Tocilizumab (any administration)	27	22%	8	24%	19	21%	0.73
Tocilizumab > 1 dose	10	8.1%	4	12%	6	6.7%	0.33
Corticosteroid (any administration)	21	17%	5	15%	16	18%	0.71
Admission to the ICU	38	31%	10	30.3%	28	31.4%	0.90