TABLE 3.
Determination of interpretive error rates associated with NCCLS MIC and zone diameter breakpoints with isolates included in this studya
| Quinolone | MIC breakpoints (μg/ml)
|
Zone breakpoints (mm)
|
Error rates (no. [%])
|
||||||
|---|---|---|---|---|---|---|---|---|---|
| S | I | R | R | I | S | VM | M | Minor | |
| Ofloxacin | ≤2 | 4 | ≥8 | ≤12 | 13–15 | ≥16 | 0 | 0 | 6 (3.7) |
| Levofloxacin | ≤2 | 4 | ≥8 | ≤13 | 14–16 | ≥17 | 0 | 0 | 2 (1.2) |
| Sparfloxacin | ≤0.5 | 1 | ≥2 | ≤15 | 16–18 | ≥19 | 3 (8.6) | 0 | 4 (2.5) |
| Grepafloxacin | ≤0.5 | 1 | ≥2 | ≤15 | 16–18 | ≥19 | 0 | 0 | 3 (1.9) |
| Trovafloxacin | ≤1 | 2 | ≥4 | ≤15 | 16–18 | ≥19 | 0 | 0 | 8 (5.0) |
Abbreviations: S, susceptible; I, intermediate; R, resistant; VM, very major error; M, major error; Minor, minor error.