Table 3.
Six-month outcomes in eyes with diabetic macular edema treated by DEX implants.
| Values | p-valuea | |
|---|---|---|
| No. of eyes | 67 | – |
| DEX implant number mean ± SD | 2.0 ± 0.8 | – |
| CFT, mean ± SD, µm | < 0.001 | |
| Baseline | 459.9 ± 146.3 | |
| 6-moa | 360.5 ± 127.4 | |
| CFT change at 6-mob | – | |
| Decreased 10% or more from baseline | 35 (52) | |
| Decreased to < 300 µm | 16 (24) | |
| BCVA, mean ± SD, logMAR | 0.35 | |
| Baseline | 0.80 ± 0.37 | |
| 6-moc | 0.79 ± 0.49 | |
| BCVA change at 6-mo | – | |
| Improved 15 ETDRS letters or more | 15 (22) | |
| Decreased 15 ETDRS letters or more | 8 (12) | |
| Stable | 38 (57) | |
| Missing | 6 (9) | |
| Lens status, phakic, No. (%) | 1.0 | |
| Baseline | 22 (33) | |
| 6-moc | 22 (33) | |
| Cataract progression | 4 (6) | |
| IOP, mean ± SD, mmHg | 0.003 | |
| Baseline | 14.2 ± 3.7 | |
| 6-moc | 17.7 ± 5.1 | |
| Elevated IOPb, No. (%) | – | |
| > 25 mmHg | 5 (9) | |
| > 35 mmHg | 2 (3) | |
| Uncontrolled glaucoma needing intervention, No. (%) | 2 (3)d | – |
aBetween the baseline and the 6-mo values.
bValid n = 58.
cValid n = 61.
dTwo eyes from the same patient with persistent elevated IOP and needed argon laser trabeculoplasty.
Abbreviation: BCVA best-corrected visual acuity, CFT central foveal thickness, DEX implant dexamethasone intravitreal implant, IOP intraocular pressure, logMAR logarithm of the minimum angle of resolution.