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. 2022 Mar 9;13:1219. doi: 10.1038/s41467-022-28727-5

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — Correlations between ⁸⁹Zr-VRC01 rSUVmean in lymph node and gut tissues on imaging day 3 compared with days on ART for viral suppressed participants are shown in a. b Correlations between ⁸⁹Zr-VRC01 rSUVmax/mean and the frequency of blood and inguinal lymph node HIV Gag P24+ CD4+ T cells as measured by flow cytometry. r and P values represent results from Spearman correlation analyses. Overall, inverse associations between tracer uptake and ART duration and a significant positive correlation between inguinal lymph node ⁸⁹Zr-VRC01 uptake and direct measures of HIV protein expression in CD4 T cells from inguinal lymph node sampling were observed. Source data are provided as a Source Data file.