Table 1.
ID | Group | ART regimen | Days on ARTa | Viral loadb | CD4+ T cell countc | Lymph node samplingd |
---|---|---|---|---|---|---|
V1 | Viremic | None | – | 74,534 | 192 | Y |
V2 | Viremic | None | – | 19,872 | 243 | Y |
V3 | Viremic | None | – | 789,705 | 36 | N |
V4 | Viremic | None | – | 106,994 | 19 | Y |
V5 | Viremic | None | – | 3499 | 500 | Y |
A1 | ART | ABC/3TC/DTG | 105 | NDe | 578 | Y |
A2 | ART | TAF/FTC/EVG/c | 3150 | ND | 526 | N |
A3 | ART | ABC/3TC/DTG | 8509 | ND | 621 | N |
A4 | ART | RPV/DTG | 640 | ND | 650 | N |
A5 | ART | TAF/FTC/EGV/DRV/c | 6863 | ND | 527 | N |
C1 | Control | – | – | – | 1503 | – |
C2 | Control | – | – | – | 908 | – |
C3 | Control | – | – | – | 762 | – |
C4 | Control | – | – | – | 702 | – |
C5 | Control | – | – | – | 158 | – |
ART antiretroviral therapy, ABC abacavir, DTG dolutegravir, 3TC lamivudine, TAF tenofovir alafenamide, RPV rilpivirine, EVG elvitegravir, c cobicistat, DRV darunavir.
aContinuous ART since last viremic episode.
bPlasma HIV-1 RNA copies/mL.
cCells/mL.
dParticipant provided additional consent to under inguinal lymph node needle biopsy.
ePlasma HIV-1 RNA not detected (limit of quantification 40 copies/mL).