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. 2022 Feb 24;13:839901. doi: 10.3389/fimmu.2022.839901

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Copyright © 2022 Yan, Wu, Yu, Kong and Cang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparison of immune microenvironment characteristics according to IRGPI status. (A, B) ESTIMATE algorithm revealed the ImmuneScore and ESTIMATEScore between IRGPI-high and IRGPI-low groups. (C) Evaluation of 22 immune cell infiltrating using the CIBERSORT method. (D) GSEA plots of immune-related pathways in comparison between IRGPI-high and IRGPI-low groups. IRGPI, immune-related gene pair index; GSEA, gene set enrichment analysis. *P < 0.05, **P < 0.01, ***P < 0.001.