Table 2.
Univariate and multivariate logistic regression analyses of mortality affected by 25(OH)D deficiency at admission in patients with COVID-19a
| Variable | Dead | Univariate analysis |
Multivariate analysis |
||
|---|---|---|---|---|---|
| OR (95% CI) | P-value | OR (95% CI) | P-value | ||
| Age (yr) | 67 (45–75) | 0.98 (0.96–1.01) | 0.115 | 0.99 (0.97–1.02) | 0.542 |
| Male | 21 (48.8) | 1.24 (0.64–2.39) | 0.526 | 1.20 (0.59–2.46) | 0.598 |
| BMI (kg/m2) | 26.1 (25.1 –34.7) | 0.98 (0.93–1.03) | 0.395 | 0.97 (0.92–1.02) | 0.233 |
| CRP (mg/dl) | 4.3 (3.3–5.6) | 1.12 (0.93–1.34) | 0.249 | 1.19 (0.97–1.47) | 0.103 |
| Severe COVID-19 | 25 (58.1) | 3.28 (1.67–6.45) | 0.001 | 2.99 (1.46–6.09) | 0.003 |
| Number of comorbidities | 1 (1–3) | 1.07 (0.83–1.38) | 0.619 | 1.13 (0.86–1.48) | 0.387 |
| 25(OH)D prior to COVID-19 deficiency | 25 (58.1) | 2.01 (1.03–3.90) | 0.041 | 1.94 (0.94–4.01) | 0.074 |
Values are presented as median (interquartile range) or number (%) unless otherwise indicated.
25(OH)D: 25-hydroxyvitamin D; COVID-19: coronavirus disease 2019; OR: odds ratio; CI: confidence interval; BMI: body mass index; CRP: C-reactive protein.
a
Multivariable analyses were conducted using logistic regression models utilizing the simultaneous method.