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. 2022 Feb 24;12:838701. doi: 10.3389/fonc.2022.838701

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Copyright © 2022 Qian, Lu, Ma, Zhang, Zhou, Wang, Shi and Zeng

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Two examples of representative MVI-negative and MVI-positive ICCs. (A–D) A 62-year-old man with a well-circumscribed MVI-negative ICC in hepatic segment II (arrows). DWI image showed target sign (A), axial arterial phase image showed rim enhancement (B), and portal vein phase image (C) and delayed phase image (D) showed the typical enhancement type of ICC: gradual and filling enhancement. (E–H) A 62-year-old man with a lobulated MVI-positive ICC in hepatic segment IV (arrows). DWI image showed hyperintensity (E), axial arterial phase image showed marginal moderate enhancement with no internal enhancement (F) and dilated bile ducts next to tumor (arrowheads), and portal vein phase image (G) and delayed phase image (H) showed the typical enhancement type of ICC: gradual and filling enhancement.