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. 2022 Feb 24;9:771679. doi: 10.3389/fcvm.2022.771679

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Copyright © 2022 Shaker, Abrams, Oppenheimer, Singer, Shaker, Fleck, Greenhawt and Grove.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Deterministic sensitivity analysis. Deterministic analyses of patients at 0.2% annual SCA risk from the societal and healthcare perspectives (A,B), patients at 1.6% annual SCA risk from the societal and healthcare perspectives (C,D), and patients at 3.5% annual SCA risk from the societal and healthcare perspectives (E,F). Cost-effectiveness is defined as care costing < $100,000 per QALY. Blue bars represent assumptions below the base case and red bars depict assumptions above the base case.