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Two-way sensitivity analysis of AED cost and SCA risk. Assuming an $800 AED cost, a SMART approach would be cost-effective (WTP, $100,000/QALY) at a 1.0% SCA risk. At an AED cost of $488, a SMART approach would be cost-effective at a threshold SCA risk of 0.77%, and at an AED cost of $176, the SMART approach becomes cost-effective at an SCA threshold risk of 0.52%.
