FIG. 4.

Cumulative growth of VNCE-LUA (○) and VC-LUA (•). CV-1 cells were infected with vaccinia virus recombinant at a multiplicity of infection of 5. At the indicated times, cells were harvested and disrupted by freezing-thawing. Viral titers in supernatant were determined by viral plaque assay on a monolayer of CV-1 cells. Data represent the means from two independent sets of experiments.