Table 8.
GRADE evidence profile.
| Quality assessment | No of patients | RR/WMD (95% CI) | P value | Quality | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| No of studies | Design | Risk of bias | Inconsistency | Indirectness | Imprecision | Other considerations | PI+WM | WM | |||
| Symptom | |||||||||||
| 17 | RCT | seriousa, b, c | No serious inconsistency | No serious indirectness | No serious imprecision | Reporting biasd | 678/743 (91.3%) | 537/716 (75%) | RR = 1.22 (1.16–1.28) |
<0.00001 | ⊕⊕°° LOW |
| 72.5% | |||||||||||
| ECG | |||||||||||
| 8 | RCT | seriousa, b, c | No serious inconsistency | No serious indirectness | No serious imprecision | Reporting biasd | 302/350 (86.3%) | 203/310 (65.5%) | RR = 1.32 (1.2–1.44) | <0.00001 | ⊕⊕°° LOW |
| 63.3% | |||||||||||
PI, Puerarin injection; WM, Western medicine; CI, Confidence interval; RR, relative risks; WMD, weight mean difference;
a
No details of random protocol were reported;
b
lack of allocation concealment;
c
Didn't report the implementation of blinding;
d
Quantitative evaluation of the included data indicated publication bias.