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. 2022 Feb 24;9:762443. doi: 10.3389/fcvm.2022.762443

Table 1.

Ratings of proposed items with medians and disagreement.

PTS diagnosis and surveillance Median Disagreement
1- The Villalta scale is recommended for diagnosis and severity classification of PTS 7 No
2- The Ginsberg scale is recommended for diagnosis and severity classification of PTS 5 Yes
3- The Brandjes scale is recommended for diagnosis and severity classification of PTS 5 No
4- The CEAP scale is recommended for diagnosis and severity classification of PTS 5 No
5- Preexisting venous insufficiency (e.g., contralateral limb) should be taken into account for classifying PTS severity after DVT 7 No
6- PTS should be assessed 1 month after the diagnosis of iliofemoral DVT 4 Yes
7- PTS should be assessed 1 month after the diagnosis of popliteal or calf DVT 4 Yes
8- PTS should be assessed 6 months after the diagnosis of iliofemoral DVT 8 No
9- PTS should be assessed 6 months after the diagnosis of popliteal or calf DVT 7 No
10- PTS should be assessed periodically (e.g., 6 months) and for at least 2 years since the diagnosis of proximal or calf DVT 7 No
PTS symptom mangement and prevention Median Disagreement
1- Graduated compression stockings (GCS) or elastic bandages are recommended for symptomatic relief in acute DVT 8 No
2- Knee length GCS (40 mmHg at the ankle) are recommended after iliofemoral DVT 6 No
3- Thigh-length GCS (40 mmHg at the ankle) are recommended after iliofemoral DVT 7 No
4- Knee length GCS (40 mmHg at the ankle) are recommended after popliteal or calf DVT 7 No
5- Thigh length GCS (40 mmHg at the ankle) are recommended after popliteal or calf DVT 4 No
6- GCS are recommended for different lengths of time according to the severity of periodically assessed PTS 7 No
7- Catheter-directed thrombolysis, with or without mechanical thrombectomy, are appropriate in patients with iliofemoral obstruction, severe symptoms, and a low risk of bleeding 7 No
8- Catheter-directed thrombolysis, with or without mechanical thrombectomy, are appropriate in patients with popliteal obstruction, severe symptoms, and a low risk of bleeding 4 No
PTS Treatment Median Disagreement
1- Thigh length GCS (30–40 mmHg at the ankle) are recommended after iliofemoral DVT 7 No
2- Knee length GCS (30–40 mmHg at the ankle) are recommended after iliofemoral DVT 6 No
3- Thigh-length GCS (30–40 mmHg at the ankle) are recommended after popliteal or calf DVT 3 No
4- Knee length GCS (30–40 mmHg at the ankle) are recommended after popliteal or calf DVT 7 No
5- Compression therapy is recommended for ulcer treatment 9 No
6- Exercise training is recommended for PTS treatment 7 No
7- Endovascular treatment (angioplasty and/or stenting) is recommended for the treatment of severe PTS 6 No
8- Oral anticoagulation is recommended after endovascular treatment with stenting 7 No
9- Long term oral anticoagulation is recommended after endovascular treatment with stenting 6 No
10- Open surgical reconstruction and hybrid operations are appropriate for the treatment of severe PTS 4 No
11- Veno-active drugs are recommended 6 No

Appropriate: panel median of 7–9, without disagreement on the final appropriateness scale: it would be considered improper care not to provide this service, and there is a reasonable chance that this procedure will benefit the patient. The benefit to the patient is not small.

Uncertain: panel median of 4–6 OR any median with disagreement; Inappropriate: panel median of 1–3, without disagreement.