Table 2.

Association of RNLS SNPs with blood pressure changes from baseline to the follow-ups.

SNP	BP (2004–2009)			BP (2004–2012)			BP (2004–2018)
	SBP change	DBP change	MAP change	SBP change	DBP change	MAP change	SBP change	DBP change	MAP change
rs10509540	0.035 a	0.521	0.809	0.434	0.459	0.946	0.274	0.902	0.590
rs7922058	0.528	0.438	0.933	0.986	0.148	0.396	0.038 a	0.626	0.966
rs999951	0.035 a	0.346	0.960	0.763	0.259	0.591	0.424	0.678	0.827
rs10887800	0.593	0.289	0.705	0.758	0.297	0.696	0.329	0.027	0.077
rs796945	0.942	0.085	0.295	0.952	0.467	0.732	0.290	0.044	0.095
rs1935582	0.613	0.006	0.051	0.932	0.149	0.398	0.451	0.001	0.019
rs7076491	0.049 a	0.732	0.754	0.897	0.367	0.657	0.784	0.658	0.906
rs2296545	0.260	0.295	0.250	0.810	0.220	0.407	0.388	0.031	0.087
rs2576178	0.490	0.564	0.575	0.919	0.303	0.577	0.561	0.028 a	0.039 a
rs17109290	0.217	0.931	0.621	0.665	0.650	0.992	0.357	0.459	0.356

All models were adjusted for the fixed effects of age, sex, and BMI, and the random effect for familial correlations. For associations that were not significant under any model, P values for an additive model are listed. All genetic models are based on the minor allele of each SNP.

BP, blood pressure; SBP, systolic blood pressure; DBP, diastolic blood pressure; MAP, mean arterial pressure; SNP, single nucleotide polymorphism.

^aRecessive model. Statistically values are presented in bold.