Table 4.
Association of individual SNPs with hypertension incidence.
SNP | Incident hypertension (2004–2009) | Incident hypertension (2004–2012) | Incident hypertension (2004–2018) | |||
---|---|---|---|---|---|---|
Effect (95% CI) | P value | Effect (95% CI) | P value | Effect (95% CI) | P value | |
rs10509540 | −0.25 (−0.92 to 0.36) | 0.428 | −0.21 (−0.75 to 0.31) | 0.435 | −0.21 (−0.52 to 0.08) | 0.157 |
rs7922058 | −0.27 (−0.94 to 0.34) | 0.397 | −0.04 (−0.56 to 0.47) | 0.871 | −0.14 (−0.43 to 0.15) | 0.348 |
rs999951 | −0.22 (−0.89 to 0.40) | 0.487 | −0.16 (−0.70 to 0.36) | 0.545 | −0.22 (−0.52 to 0.08) | 0.155 |
rs10887800 | 0.15 (−0.38 to 0.70) | 0.589 | 0.10 (−0.35 to 0.54) | 0.668 | 0.15 (−0.09 to 0.40) | 0.217 |
rs796945 | −0.29 (−0.82 to 0.21) | 0.269 | −0.22 (−0.64 to 0.20) | 0.304 | −0.24 (−0.48 to −0.01) | 0.042 |
rs1935582 | −0.23 (−0.76 to 0.30) | 0.391 | −0.30 (−0.75 to 0.14) | 0.182 | −0.29 (−0.54 to −0.04) | 0.023 |
rs7076491 | −0.35 (−1.18 to 0.38) | 0.374 | −0.23 (−0.86 to 0.37) | 0.458 | −0.20 (−0.54 to 0.13) | 0.242 |
rs2296545 | 0.51 (−0.00 to 1.08) | 0.060 | 0.11 (−0.32 to 0.55) | 0.610 | 0.18 (−0.06 to 0.42) | 0.138 |
rs2576178 | −0.53 (−1.06 to −0.05) | 0.035 | −0.18 (−0.60 to 0.22) | 0.378 | −0.24 (−0.46 to −0.01) | 0.043 |
rs17109290 | −0.65 (−1.63 to 0.16) | 0.147 | −0.25 (−0.91 to 0.36) | 0.428 | −0.22 (−0.57 to 0.11) | 0.197 |
All models were adjusted for the fixed effects of age, sex, and BMI, and the random effect for familial correlations. SNP, single nucleotide polymorphism; CI, confidence interval. Statistically values are presented in bold.