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. 2022 Feb 24;9:800427. doi: 10.3389/fcvm.2022.800427

Table 4.

Association of individual SNPs with hypertension incidence.

SNP Incident hypertension (2004–2009) Incident hypertension (2004–2012) Incident hypertension (2004–2018)
Effect (95% CI) P value Effect (95% CI) P value Effect (95% CI) P value
rs10509540 −0.25 (−0.92 to 0.36) 0.428 −0.21 (−0.75 to 0.31) 0.435 −0.21 (−0.52 to 0.08) 0.157
rs7922058 −0.27 (−0.94 to 0.34) 0.397 −0.04 (−0.56 to 0.47) 0.871 −0.14 (−0.43 to 0.15) 0.348
rs999951 −0.22 (−0.89 to 0.40) 0.487 −0.16 (−0.70 to 0.36) 0.545 −0.22 (−0.52 to 0.08) 0.155
rs10887800 0.15 (−0.38 to 0.70) 0.589 0.10 (−0.35 to 0.54) 0.668 0.15 (−0.09 to 0.40) 0.217
rs796945 −0.29 (−0.82 to 0.21) 0.269 −0.22 (−0.64 to 0.20) 0.304 −0.24 (−0.48 to −0.01) 0.042
rs1935582 −0.23 (−0.76 to 0.30) 0.391 −0.30 (−0.75 to 0.14) 0.182 −0.29 (−0.54 to −0.04) 0.023
rs7076491 −0.35 (−1.18 to 0.38) 0.374 −0.23 (−0.86 to 0.37) 0.458 −0.20 (−0.54 to 0.13) 0.242
rs2296545 0.51 (−0.00 to 1.08) 0.060 0.11 (−0.32 to 0.55) 0.610 0.18 (−0.06 to 0.42) 0.138
rs2576178 −0.53 (−1.06 to −0.05) 0.035 −0.18 (−0.60 to 0.22) 0.378 −0.24 (−0.46 to −0.01) 0.043
rs17109290 −0.65 (−1.63 to 0.16) 0.147 −0.25 (−0.91 to 0.36) 0.428 −0.22 (−0.57 to 0.11) 0.197

All models were adjusted for the fixed effects of age, sex, and BMI, and the random effect for familial correlations. SNP, single nucleotide polymorphism; CI, confidence interval. Statistically values are presented in bold.