TABLE 1.
Overview of the commercially available nanomedicines in the EU (Van Trier, 2021).
| Nanomedicine class | Active substance | Brand name | Pharmaceutical form | Indication |
|---|---|---|---|---|
| Nanoparticles | Albumine-particle | Abraxane | Powder for suspension | Breast neoplasm |
| Bound paclitaxel | Non–small-cell lung cancer | |||
| Pancreatic neoplasms | ||||
| Y90 ibritumab tiuxetan | Zevalin | Solution for infusiion | Folicullar lymphoma | |
| Glatirimer acetate | Copaxone | Solution for injection | Multiple sclerosis | |
| Liposome | Cytarabine | DepoCyt | Suspension for injection | Lymphomatous meningitis |
| Mifamurtide | *Mepact | Powder for concentrate for dispersion for infusion | Osteosarcoma | |
| Morphine | DepoDur | Suspension for injection | Pain | |
| Doxorubicin hydrochloride | Caelyx | Concentrate for suspension for infusion | Kaposi sarcoma | |
| Doxorubicin hydrochloride | Myocet | Powder, dispersion, and solvent for concentrate for infusion | Metastatic breast cancer | |
| Amphotericine B | AmBisome | Powder for solution for infusion | Fungal infection | |
| Daunorubicin | DaunoXome | Concentrate for solution for infusion | HIV-related Kaposi sarcoma | |
| Cytaribine daunorubicin | *Vyxeos | Concentrate for solution for infusion | Leukemia | |
| Amikacinesulfaat | *Arikayce lyposomal | Nebulizer dispersion | NTM lung diseases | |
| Irinotecan | *Onyvide | Solution for infusion | Pancreatic cancer | |
| Lipid nanoparticles | mRNA encoding for SARS-CoV-2 Spike protein | Comirnaty | Concentrate for dispersion for injection | COVID-19 |
| Patisian | Onpattro | Intravenous infusion | Polyneuropathy of hereditary TTR-mediated amyloidosis (hATTR) | |
| ChAdOx1-S | Vaxzevria | Suspension for injection | COVID-19 | |
| Encoding the | ||||
| SARSCoV-2 | ||||
| Spike glycoprotein | ||||
| mRNA encoding | Spikevax | Dispersion for injection | COVID-19 | |
| for SARS-CoV-2 | ||||
| Spike protein | ||||
| Nanocrystals | Paliperidone palmitate | Xeplion | Prolonged release suspension for injection | Schizophrenia |
| Onlazapine pamoate | Zypadhera | Powder and solvent for prolonged release suspension for injection | Schizophrenia | |
| Aprepitant | Emend | Capsule | Nausea and vomiting | |
| Fenofibrate | Tricor | Tablet | Hyperlipidaemia | |
| Lipanthyl | ||||
| Lipidil | ||||
| Iron-carbohydrates | Feric carboxymaltose | Ferinject | Solution for infusion | Iron deficiency |
| Iron (3) isomaltoside | Monofer | Solution for infusion | Iron deficiency | |
| Iron (3)-hydroxide | Ferrosat | Solution for infusion | Iron deficiency | |
| Dextran complec |
*Designated orphan medicine