Table 1.
Clinicopathological characteristics of patients with nmRCC.
| All | Training set | Validation set | ||
|---|---|---|---|---|
| N = 27,073 | N = 18,990 | N = 8,083 | P | |
| Age | 52.4 (5.61) | 52.4 (5.61) | 52.4 (5.61) | 0.724 |
| Race | 0.651 | |||
| White | 20,993 (77.5%) | 14,754 (77.7%) | 6,239 (77.2%) | |
| Black | 4,288 (15.8%) | 2,985 (15.7%) | 1,303 (16.1%) | |
| Other | 1,792 (6.62%) | 1,251 (6.59%) | 541 (6.69%) | |
| Sex | 0.644 | |||
| Male | 17,531 (64.8%) | 12,314 (64.8%) | 5,217 (64.5%) | |
| Female | 9,542 (35.2%) | 6,676 (35.2%) | 2,866 (35.5%) | |
| Year of diagnosis | 0.718 | |||
| 2010-2014 | 14,784 (54.6%) | 10,356 (54.5%) | 4,428 (54.8%) | |
| 2015-2018 | 12,289 (45.4%) | 8,634 (45.5%) | 3,655 (45.2%) | |
| Marriage | 0.152 | |||
| No | 11,058 (40.8%) | 7,810 (41.1%) | 3,248 (40.2%) | |
| Married | 16,015 (59.2%) | 11,180 (58.9%) | 4,835 (59.8%) | |
| Grade | 0.143 | |||
| I | 2,747 (10.1%) | 1,894 (9.97%) | 853 (10.6%) | |
| II | 12,412 (45.8%) | 8,797 (46.3%) | 3,615 (44.7%) | |
| III | 6,048 (22.3%) | 4,196 (22.1%) | 1,852 (22.9%) | |
| IV | 928 (3.43%) | 651 (3.43%) | 277 (3.43%) | |
| Unknown | 4,938 (18.2%) | 3,452 (18.2%) | 1,486 (18.4%) | |
| T | 0.172 | |||
| T1a | 14,571 (53.8%) | 10,178 (53.6%) | 4,393 (54.3%) | |
| T1b | 6,105 (22.6%) | 4,314 (22.7%) | 1,791 (22.2%) | |
| T2 | 5,015 (18.5%) | 3,557 (18.7%) | 1,458 (18.0%) | |
| T3 | 1,350 (4.99%) | 917 (4.83%) | 433 (5.36%) | |
| T4 | 32 (0.12%) | 24 (0.13%) | 8 (0.10%) | |
| Laterality | 0.784 | |||
| Left | 13,090 (48.4%) | 9,171 (48.3%) | 3,919 (48.5%) | |
| Right | 13,983 (51.6%) | 9,819 (51.7%) | 4,164 (51.5%) | |
| Histologic type | 0.866 | |||
| Clear cell | 17,534 (64.8%) | 12,270 (64.6%) | 5,264 (65.1%) | |
| Papillary | 4,011 (14.8%) | 2,832 (14.9%) | 1,179 (14.6%) | |
| Chromophobe | 1,776 (6.56%) | 1,249 (6.58%) | 527 (6.52%) | |
| Not classified | 3,752 (13.9%) | 2,639 (13.9%) | 1,113 (13.8%) | |
| Tumor size | 46.0 (31.9) | 46.1 (31.8) | 45.7 (32.1) | 0.323 |
| Surgery | 0.843 | |||
| No | 1,161 (4.29%) | 811 (4.27%) | 350 (4.33%) | |
| Local tumor excision | 1,042 (3.85%) | 742 (3.91%) | 300 (3.71%) | |
| Partial nephrectomy | 11,750 (43.4%) | 8,222 (43.3%) | 3,528 (43.6%) | |
| Radical nephrectomy | 13,120 (48.5%) | 9,215 (48.5%) | 3,905 (48.3%) | |
| Chemotherapy | 0.266 | |||
| No/unknown | 26,702 (98.6%) | 18,740 (98.7%) | 7,962 (98.5%) | |
| Yes | 371 (1.37%) | 250 (1.32%) | 121 (1.50%) | |
| Radiation | 0.531 | |||
| No/unknown | 27,015 (99.8%) | 18,952 (99.8%) | 8,063 (99.8%) | |
| Yes | 58 (0.21%) | 38 (0.20%) | 20 (0.25%) |