Table 2.

Univariate and multivariate analyses of CSS in training set.

	Univariate			Multivariate
	HR	95%CI	P	HR	95%CI	P
Age	1.05	1.03-1.06	<0.001	1.036	1.021-1.051	<0.001
Race
White	Reference
Black	1.075	0.911-1.267	0.391
Other	0.998	0.774-1.288	0.989
Sex
Male	Reference			Reference
Female	0.7	0.59-0.82	<0.001	0.859	0.729-1.013	0.07
Year of diagnosis
2010-2014	Reference
2015-2018	0.89	0.73-1.08	0.225
Marriage
No	Reference
Married	0.88	0.76-1.02	0.088
Grade
I	Reference			Reference
II	1.238	0.895-1.714	0.198	1.082	0.723-1.618	0.702
III	4.17	3.042-5.717	<0.001	2.468	1.658-3.673	<0.001
IV	14.972	10.711-20.93	<0.001	5.054	3.293-7.759	<0.001
Unknown	3.14	2.26-4.363	<0.001	1.508	0.99-2.297	0.055
T
T1a	Reference			Reference
T1b	1.982	1.628-2.413	<0.001	1.377	1.065-1.779	0.015
T2	6.509	5.565-7.613	<0.001	3.328	2.612-4.241	<0.001
T3	11.057	8.482-14.412	<0.001	4.861	3.46-6.83	<0.001
T4	74.388	36.566-151.329	<0.001	21.349	9.677-47.103	<0.001
Laterality
Left	Reference
Right	0.93	0.81-1.08	0.345
Histologic type
Clear cell	Reference
Papillary	0.909	0.758-1.091	0.308
Chromophobe	0.366	0.245-0.545	<0.001
Not classified	1.414	1.209-1.655	<0.001
Tumor size	1.01	1.01-1.01		1.004	1.003-1.005	<0.001
Surgery
No	Reference			Reference
Local tumor excision	0.174	0.111-0.273	<0.001	0.254	0.151-0.427	<0.001
Partial nephrectomy	0.08	0.062-0.103	<0.001	0.082	0.059-0.115	<0.001
Radical nephrectomy	0.421	0.345-0.514	<0.001	0.172	0.128-0.232	<0.001