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. 2022 Mar 3;13:100173. doi: 10.1016/j.metop.2022.100173

Table 4.

Studies included in the 2017 and 2019 Meta-analyses of Studies Examining Skeletal Health in Transgender Individuals.

Studies included in 2017 Systematic Review [35]
Study Country Design Patients N Mean Age (years) Duration
Dittrich 2005 Germany Cohort Transgender women 60 38.37 24 mos
Klink 2015 Netherlands Cohort Transgender women/Transgender men 15/19 14.9/15 7.1/6.9 yrs
Mueller 2011 Germany Cohort Transgender women 84 36.3 24 mos
Mueller 2010 Germany Cohort Transgender men 45 30.4 12 and 24 mos
Pelusi 2014 Italy Cohort Transgender men 45 29.4 12 mos
Reutraku1998 Thailand Cohort Transgender women 11 21.2 <24 mos
Sosa 2003 Spain Cohort Transgender women 17/27 24.1/43 >24 mos
Turner2004 USA Cohort Transgender men 8 33.1 24 mos
VanCaenegem 2015 Belgium Cohort Transgender men/Transgender women 23/49 27/33 12 and 24 mos
VanCaenegem 1996 Belgium Cohort Transgender women/Transgender men 56/35 33/25 12 mos
VanCaenegem 1998 Netherlands Cohort Transgender women/Transgender men 20/19 25.4/25 45.5/38.2 mos
Wierckx 2014 Belgium Cohort Transgender women 47/6 31.7/19.3 12 mos
Wierckx 2014
Belgium
Cohort
Transgender men
27/26
27.3/21.7
12 mos
Additional Studies included in 2019 Systematic Review [36]
Study
Country
Design
Patients
N
Mean Age (years)
Duration
Haraldsen 2007 Norway Cohort Transgender men/Transgender women 21/12 25.1/29.3 12 mos
Wiepjes 2017 Belgium Cohort Transgender men/Transgender women 199/231 23.9/22.5 12 mos
Gava 2016 Italy Cohort Transgender women 40 32.9 12 mos
Fighera 2018 Brazil Cohort Transgender women 46 33.7 31 mos
Van Kesteren 1996 Netherlands Cohort Transgender men/Transgender women 35/56 25/33 12 mos
Van Kesteren 1998 Netherlands Cohort Transgender men/Transgender women 19/20 25/25.4 38.2 mos

Abbreviations: mos, months; yrs, years.

Adapted and expanded from Singh-Ospina N et al. J Clin Endocrinol Metab. 2017 [35].