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. 2022 Feb 24;10:852210. doi: 10.3389/fchem.2022.852210

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Copyright © 2022 Lu, Chen, Khan, Brassard, Arutyunova, Lamer, Vuong, Fischer, Young, Vederas and Lemieux.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparison of FIPV M^pro and SARS-CoV-2 M^pro bound to GC373. (A) Crystal structure of FIPV M^pro with GC373 in lavender (PDB: 7SNA) and (B) SARS-CoV-2 M^pro with GC373 in tan (PDB: 6WTK).