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. 2022 Feb 24;13:821166. doi: 10.3389/fneur.2022.821166

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Copyright © 2022 Petro, Agarkova, Esmael, Dunigan, Van Etten and Pattee.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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ATCV-1 SOD1 and expression of immune factors from RAW264.7 Lucia cells. (A) IL-6, (B) IL-10, (C) Nitric Oxide (NO), and (D) Secreted Luciferase driven by an ISRE promoter in supernatants of RAW264.7 cells transfected with pEGFP empty vector or an expression vector coding for ATCV-1 SOD1 and then stimulated with 10 ug/ml poly I:C (IC) with or without 50 ng/ml mouse recombinant IFN-gamma (IFN-γ). Representative data from three experiments with means ± standard error; n = 4 separate transfections for each experiment. * indicates significantly different from cells transfected with empty vector.