Figure 4.
Analysis of the antitumor activity of IL13 (4MS)-EphA2 scFv-TanCAR CD8+ T cells in a glioblastoma animal model
(A) The detection of tumor progression by bioluminescence imaging. (B) The growth curve of tumors from the different groups treated with CAR-T cells. The tumor volume data are represented as mean ± standard deviation (mm3). (C) Photographs of tumors from different groups treated with CAR-T cells. On day 28 after tumor inoculation, tumors were resected immediately after euthanasia, and photographs of three samples from each group are shown. (D) Quantification of tumors from different groups treated with CAR-T cells by tumor weight. The tumor weight data are represented as mean ± standard deviation (mg). Statistically significant differences are indicated: ∗∗p < 0.01. TanCAR stands for IL13 (4MS)-EphA2 scFv-TanCAR.