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. 2022 Feb;10(4):214. doi: 10.21037/atm-22-358

Figure 1.

Figure 1

Relationship between TMB and age, MSI, or tumor types in blood samples. In blood samples, (A) TMB in age 1 (n=157, age ≤56 years old), age 2 (n=177, 56< age <68 years old) and age 3 (n=161, age ≥68 years old) groups. (B) MSI-H (n=12) and MSS/MSI-L (n=484), and (C) MSI ratio (%) in blood samples. (D,E) TMB among ASC (n=0), LUAD (n=131), LUSC (n=7), NSCLC (n=3), and SCLC (n=3) samples. ns: no significance, P>0.05; *P<0.05, ***P<0.001. TMB, tumor mutational burden; MSI, microsatellite instability; ASC, adenosquamous carcinoma; LUAD, lung adenocarcinoma; LUSC, lung squamous cell carcinoma; NSCLC, non-small cell lung cancer; SCLC, small cell lung cancer.