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. 2022 Feb;10(4):214. doi: 10.21037/atm-22-358

Figure 2.

Figure 2

Relationship between TMB and age, MSI, or tumor types in tissue samples. In tissue samples, (A) TMB between age 1 (n=489, age ≤53 years old), age 2 (n=497, 53< age <65 years old), and age 3 (n=512, age ≥65 years old) groups. (B) MSI-H (n=33) and MSS/MSI-L (n=1357), and (C) MSI ratio (%) in tissue samples are exhibited. (D) TMB among ASC (n=1), LUAD (n=222), LUSC (n=26), NSCLC (n=3), and SCLC (n=8) samples. (E) TMB between blood samples (n=4) and tissue samples (n=20) in colorectal cancer. ns: no significance, P>0.05; ****P<0.0001. TMB, tumor mutational burden; MSI, microsatellite instability; ASC, adenosquamous carcinoma; LUAD, lung adenocarcinoma; LUSC, lung squamous cell carcinoma; NSCLC, non-small cell lung cancer; SCLC, small cell lung cancer.