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. 2022 Feb;10(4):204. doi: 10.21037/atm-22-6

Figure 8.

Figure 8

Changes in the protein levels of ER stress-related factors in PDLSCs after stimulation with different concentrations of D-glucose. (A) The protein levels of ER stress-related factors after D-glucose stimulation at different concentrations, as detected by western blot. Quantification of the GRP78 (B), ATF6 (C), PERK (D), and XBP1 (E) protein levels, using β-actin for internal reference. *, P<0.05, **, P<0.01, ***, P<0.001 compared with 8 mmol/L D-glucose stimulation group at the same time point. #, P<0.05, ##, P<0.01, ###, P<0.001 compared with 6 hours after stimulation with the same D-glucose concentration. ER, endoplasmic reticulum; PDLSCs, periodontal ligament stem cells; GRP78, glucose regulated protein 78; ATF6, activating transcription factor 6; PERK, double-stranded RNA-activated protein kinase (PKR) like endoplasmic reticulum kinase; XBP1, X box-binding protein 1.