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. 2022 Feb;10(4):224. doi: 10.21037/atm-21-6909

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2022 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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SENP1 expression in lung cancer and its correlation with the survival of lung cancer patients. (A) The Gene Expression profiling interactive analysis (GEPIA) database analyzed the overall gene expression in lung cancer (with partial results). (B) The GEPIA database analysis showed that SENP1 was highly expressed in lung cancer (the red boxplot is tumor, and the black boxplot is normal). (C) Immunohistochemical (IHC) staining for SENP1 in 35 pairs of lung cancer samples (left), and the H-score statistical analysis was conducted for SENP1 (right). (D) Oncomine analyzed the association of SENP1 expression with overall survival (OS) and free progress (FP) in patients with lung cancer (n=1,145). (E) Oncomine analyzed the association of SENP1 expression with OS and FP in patients with lung cancer after cisplatin chemotherapy (n=478).