Table 2. Characteristics and distribution of breast cancer patients in the TCGA-BRCA cohort.
Clinicopathological features | Expression of miR-93-5p | Survival | |||||
---|---|---|---|---|---|---|---|
Low (n=71) | High (n=29) | P | Alive (n=77) | Dead (n=23) | P | ||
Age | NS | <0.05 | |||||
<60 years | 49 | 19 | 57 | 11 | |||
>60 years | 22 | 10 | 20 | 12 | |||
Lymph metastasis | NS | <0.05 | |||||
Present | 34 | 16 | 33 | 17 | |||
Absent | 37 | 13 | 44 | 6 | |||
Pathological grade | NS | NS | |||||
Grade II | 51 | 17 | 55 | 13 | |||
Grade II–III | 20 | 12 | 22 | 10 | |||
T stage | NS | NS | |||||
T1/2 | 71 | 27 | 75 | 23 | |||
T3/4 | 0 | 2 | 2 | 0 | |||
TNM stage | <0.01 | <0.01 | |||||
I–II | 49 | 11 | 58 | 9 | |||
III | 22 | 18 | 19 | 14 | |||
Relapse | NS | <0.0001 | |||||
Yes | 19 | 9 | 11 | 17 | |||
No | 52 | 20 | 66 | 6 | |||
ER | NS | <0.01 | |||||
+ | 53 | 18 | 60 | 11 | |||
− | 18 | 11 | 17 | 12 | |||
PR | NS | NS | |||||
+ | 41 | 13 | 44 | 10 | |||
− | 30 | 16 | 33 | 13 | |||
HER2 | NS | NS | |||||
+ | 15 | 4 | 13 | 6 | |||
− | 56 | 25 | 64 | 17 | |||
TNBC | NS | NS | |||||
Yes | 12 | 8 | 12 | 8 | |||
No | 49 | 21 | 65 | 15 | |||
Expression of miR-93-5p | – | NS | |||||
Low | – | – | 55 | 16 | |||
High | – | – | 22 | 7 |
NS, not significant; TNBC, triple negative breast cancer; ER, estrogen receptor; PR, progesterone receptor.