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. 2022 Feb 23;7(1):e34465. doi: 10.2196/34465

Table 1.

Variables, pretreatment, and 3 months post–glycemic excursion minimization intervention.

Variable				Pretreatment		3 months post–glycemic excursion minimization		P value		Baseline correlation with change in hemoglobin A_1c levels		Change in correlation with change in hemoglobin A_1c levels
Primary outcome variables, mean (SD)
	Hemoglobin A_1c levels (%)			8.0 (1.6)		6.2 (1.1)		<.001^a			–0.755^b
	Metformin (mg/day)			0 (0)		133 (516)		.33					–0.219
Mechanism variables
	Continuous glucose monitoring data, unblinded weeks 1 and 18, mean (SD)
		Percentage of time when continuous glucose monitoring values were >140 mg/dL	23.9 (28.9)		14.5 (22)		.03			–0.012		–0.086
		Glucose variability	22.4 (10.1)		20.2 (8.3)		.08			0.132		–0.208
	High-carbohydrate foods			39.6 (21.9)		10.3 (6.8)		<.001^a			–0.243		0.238
	Low-carbohydrate foods			50.2 (20.8)		48.6 (20.0)		.69			–0.413		0.635^c
Secondary benefits, mean (SD)
	Diabetes knowledge			15.5 (3.0)		15.9 (3.0)		.53			0.061		0.555^c
	Diabetes empowerment			31.0 (5.9)		34.6 (3.8)		.06			–0.253		0.251
	Diabetes distress, emotional			2.2 (0.8)		1.8 (1.0)		.10			–0.580^c		0.015
	Diabetes distress, regimen			2.8 (1.4)		1.8 (0.9)		.03			0.363		–0.052
	Depressive symptoms			6.1 (4.5)		2.3 (3.9)		.001^a			0.400		0.132
	BMI			36.5 (8.1)		34.4 (8.2)		.002^a			0.013		0.333

^aSignificant with the Benjamini-Hochberg procedure.

^bCorrelation with P<.01.

^cCorrelation with P<.05.