TABLE 1.
Distribution of erythromycin and clarithromycin MICs for the mutations observed
Mutation | No. of strains | Erythromycin MIC (μg/ml) | Clarithromycin MIC (μg/ml) |
---|---|---|---|
A2142C | 2 | >256 | >256 |
A2142G | 10 | >256 | >256 |
A2143G | 7 | >256 | >256 |
1 | >256 | 256 | |
2 | >256 | 128 | |
3 | >256 | 64 | |
4 | >256 | 32 | |
3 | >256 | 16 | |
2 | >256 | 8 | |
1 | >256 | 4 | |
2 | >256 | 2 | |
2 | >256 | 1 | |
1 | >256 | 0.5 | |
2 | >256 | 0.016 | |
Wild-type sequence | 1 | 0.5 | <0.016 |
2 | 0.25 | <0.016 | |
1 | 0.125 | 0.023 | |
6 | 0.125 | <0.016 | |
4 | 0.06 | <0.016 | |
9 | 0.032 | <0.016 | |
4 | 0.016 | <0.016 | |
2 | <0.016 | <0.016 |