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. 1999 Feb;43(2):374–376. doi: 10.1128/aac.43.2.374

TABLE 1.

Distribution of erythromycin and clarithromycin MICs for the mutations observed

Mutation No. of strains Erythromycin MIC (μg/ml) Clarithromycin MIC (μg/ml)
A2142C 2 >256 >256
A2142G 10 >256 >256
A2143G 7 >256 >256
1 >256 256
2 >256 128
3 >256 64
4 >256 32
3 >256 16
2 >256 8
1 >256 4
2 >256 2
2 >256 1
1 >256 0.5
2 >256 0.016
Wild-type sequence 1 0.5 <0.016
2 0.25 <0.016
1 0.125 0.023
6 0.125 <0.016
4 0.06 <0.016
9 0.032 <0.016
4 0.016 <0.016
2 <0.016 <0.016