Table 1. Baseline Characteristics for Differentiation Between Type 2 Myocardial Infarction (T2MI) and Type 1 Myocardial Infarction (T1MI).
| Characteristic | No. (%) | P valuea | ||
|---|---|---|---|---|
| All patients (N = 6253) | T2MI (n = 251) | T1MI (n = 1027) | ||
| Age, median (IQR), y | 61 (48-74) | 71 (60-80) | 69 (57-79) | .25 |
| Sex | ||||
| Male | 4175 (67) | 161 (64) | 760 (74) | .002 |
| Female | 2078 (33) | 90 (36) | 267 (26) | |
| BMI, median (IQR)b | 26 (24-30) | 26 (24-29) | 27 (24-29) | .32 |
| Risk factors | ||||
| Hypertension | 3700 (59) | 193 (77) | 757 (74) | .30 |
| Hypercholesterolemia | 2937 (47) | 132 (53) | 629 (61) | .01 |
| Diabetes | 1062 (17) | 65 (26) | 261 (25) | .88 |
| Current smoking | 1580 (25) | 49 (20) | 272 (26) | .02 |
| History of smoking | 2312 (37) | 99 (39) | 418 (41) | .72 |
| Positive family history of CAD | 944 (15) | 23 (9) | 162 (16) | .007 |
| Medical history | ||||
| Coronary artery disease | 1966 (31) | 104 (41) | 407 (40) | .60 |
| Myocardial infarction | 1400 (22) | 67 (27) | 311 (30) | .26 |
| Myocardial revascularization | 1641 (26) | 77 (31) | 324 (32) | .79 |
| Peripheral artery disease | 326 (5.2) | 25 (10) | 103 (10) | .97 |
| Ischemic/hemorrhagic stroke | 324 (5.2) | 22 (8.8) | 80 (7.8) | .61 |
| Vital parameters, median (IQR) | ||||
| SBP, mm Hg | 140 (125-156) | 135 (117-153) | 144 (127-161) | <.001 |
| Heart rate, beats per minute | 76 (66-89) | 89 (73-119) | 76 (65-88) | <.001 |
| Oxygen saturation, % | 98 (97-100) | 98 (96-99) | 98 (96-99) | .36 |
| Biochemistry, median (IQR) | ||||
| hs-cTn T, ng/L | ||||
| Baseline | 8 (4-20) | 30 (17-59) | 63 (29-291) | <.001 |
| Absolute change within 1 h | 1 (0-2) | 5 (2-13) | 11 (4-39) | <.001 |
| Peak value within 6 h | 9 (5-24) | 40 (26-84) | 113 (45-332) | <.001 |
| Hemoglobin, g/dL | 14.3 (13.2-15.3) | 14.1 (12.5-15.3) | 14.3 (13.0-15.4) | .04 |
| BNP, pg/mLc | 142 (44-509) | 1036 (201-3463) | 558 (169-1648) | .20 |
| Creatinine clearance, mL/min/1.73 m2 | 84 (68-100) | 70 (52-90) | 76 (61-94) | .001 |
Abbreviations: BMI, body mass index; BNP, brain-type natriuretic peptide; CAD, coronary artery disease; hs-cTn, high-sensitivity cardiac troponin; SBP, systolic blood pressure.
SI conversion factor: To convert hemoglobin to g/L, multiply by 10; BNP to ng/L multiply by 1.
a
P values for comparison between T2MI and T1MI.
b
Calculated as weight in kilograms divided by height in meters squared.
c
Data available in 1225 patients overall, 51 patients with T2MI, and 221 patients with T1MI.