Fig. 6.

LMH001 protection against AngII-induced damages to aortic elastin and collagen and inflammation. a. Verhoeff-Van Gieson staining of elastin (black). The results were expressed as ratios of elastin area/total vessel area. b. Masson's trichrome staining of collagen (blue). The results were expressed as fold changes of vehicle control values. c. Immunofluorescence detection of CD68 positive leucocyte (red) infiltration in aortic walls. Nuclei were labelled by DAPI (blue) to visualize the cells. *P < 0.05 for AngII values versus control values in the same category labelled underneath. †P < 0.05 for indicated LMH001 values versus AngII vehicle values. n = 9 mice/group. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)