Fig. 7.

LMH001 inhibition of AngII-induced Nox2 expression, ERK1/2 activation and CD45 positive cell infiltration in aortic walls detected by immunofluorescence. a. Nox2 expression (red) and ERK1/2 phosphorylation (green). b. Nox2 expression (green) and CD45 (red) positive leucocyte infiltration in aortic walls. Nuclei were labelled by DAPI (blue) to visualize the cells. Fluorescence intensities (Fluo-intensity) were quantified. *P < 0.05 for indicated values versus control values in the same category labelled underneath. †P < 0.05 for indicated LMH001 values versus AngII vehicle values. n = 9 mice/group. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)