Table 1.
Parameter | Unit | NCA (0–30 min) |
---|---|---|
C0 | ng/mL | 54593.44 |
Cmax | ng/mL | 27271.79 |
AUC0-∞ | ng/mL/h | 1759.75 |
t1/2 | h | 0.042 |
Kel | 1/h | 16.55 |
CL | mL/h/kg | 5682.63 |
Vd | mL/kg | 343.43 |
NCA: non-compartmental analysis (R2 = 0.9575). C0: extrapolated plasma concentration at time 0; Cmax: maximum plasma concentration; AUC0-∞: Area under the curve from time 0 extrapolated to infinite time; t1/2: terminal half-life; Kel: elimination rate constant; CL: plasma clearance; Vd: volume of distribution.