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. 2022 Mar 3;51:102269. doi: 10.1016/j.redox.2022.102269

Table 1.

Pharmacokinetic characterization of LMH001.

Parameter Unit NCA (0–30 min)
C0 ng/mL 54593.44
Cmax ng/mL 27271.79
AUC0-∞ ng/mL/h 1759.75
t1/2 h 0.042
Kel 1/h 16.55
CL mL/h/kg 5682.63
Vd mL/kg 343.43

NCA: non-compartmental analysis (R2 = 0.9575). C0: extrapolated plasma concentration at time 0; Cmax: maximum plasma concentration; AUC0-∞: Area under the curve from time 0 extrapolated to infinite time; t1/2: terminal half-life; Kel: elimination rate constant; CL: plasma clearance; Vd: volume of distribution.