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. 2022 Mar 7;28(9):918–932. doi: 10.3748/wjg.v28.i9.918

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©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

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Apoptosis was induced in Caco2 cells after hypoxia/reoxygenation treatment. A: Cell viability was tested using the CCK8 kit on different times after the hypoxia/reoxygenation (H/R) treatment, ^aP < 0.01 and ^bP < 0.001 vs control (n = 3); B: The quantification data of apoptosis tested by the TUNEL at different times after the H/R treatment, ^bP < 0.001 vs control (n = 3); C: Representative Western blotting and quantification data for cell apoptotic proteins Bcl-2 and Bax at different times after the H/R treatment. Data are presented as mean ± SD, ^aP < 0.01 and ^bP < 0.001 vs control (n = 3). NS: No significant difference; H/R: Hypoxia/reoxygenation.