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Genomic features of ctDNA dynamically changed in colorectal cancer patients received anti-EGFR therapies. (A) The ctDNA genomic features for all specimens at baseline, remission, and progression in colorectal cancer patients who received cetuximab-targeted therapy. (B) The clonal and subclonal landscapes in mCRC patient at baseline, remission, and progression. Gain: segments with log ratio more than 3 times of standard deviation of all segment level were considered as “gain”.
