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. 2022 Feb 24;16:838594. doi: 10.3389/fnins.2022.838594

Figure 1.

Figure 1

Tridimensional human brain-derived models comparative. (A) Summarized schematics of human brain organoids (Created with BioRender.com) and slice cultures preparation processes. (B) Number of research articles per year between 2000 and 2020. Blue bars correspond to the documents retrieved with “human; brain; slice; culture; disease” as search terms. The total number of documents was 591 (first document retrieved published in 1987). Orange bars correspond to the documents retrieved with “human; brain; model; organoid; disease” as search terms. Total number of documents equals 359 (one excluded due to retraction). The Scopus database was used.