Table 1. Sulfonylureas 1–12 and Their Chemical Stability.

^aAreas under the curve (AUCs) of the chromatograms after 8 h of incubation at the indicated pH were determined for the test compound and the internal standard. Ratios were calculated as a measure of stability using eq S1 (Supporting Information).

^bRatio values at nine different time points were plotted versus incubation time and fitted to the equation of exponential decay. Half-lives, t_1/2, were calculated using eq S2 (Supporting Information).

^cNot detectable; no decomposition observed within 8 h.