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Schematic representation of an integrated mathematical model coupling the blood flow within the lamina cribrosa, described as a three-dimensional porous medium, with the blood flow in the retinal, choroid and retrobulbar circulation, described as a lumped parameter network. Image reproduced from (Sala et al., 2018b), with permission. The model is also available as a web-based app for training and research purposes (_S1_Reference281Sala et al. 2018b, 2019a; Sala, 2019b).
