Table 1.
Insulin resistance profile and lipid profile in the blood
| Parameters | Week 12 | Week 28 | ||||||
|---|---|---|---|---|---|---|---|---|
|
ND (n = 6) |
PDM (n = 30) |
ND (n = 6) |
PDM (n = 6) |
PDMCR-SM (n = 6) |
PDMCR-L (n = 6) |
PDMEX-SM (n = 6) |
PDMEX-L (n = 6) |
|
| Fasting glucose (mg/dL) | 107.90 ± 6.35 | 183.82 ± 5.64* | 183.45 ± 7.82 | 228.86 ± 15.70* | 164.88 ± 12.56† | 143.54 ± 6.44*† | 183.15 ± 19.67†§ | 186.89 ± 4.32†§ |
| Fasting insulin (mU/mL) | 4.55 ± 0.67 | 7.25 ± 0.64* | 5.55 ± 0.84 | 9.60 ± 1.29* | 5.32 ± 0.57† | 5.45 ± 1.02† | 5.81 ± 1.55† | 6.02 ± 1.08† |
| HOMA-IR | 1.24 ± 0.23 | 3.09 ± 0.32* | 3.38 ± 0.39 | 5.68 ± 0.68* | 2.51 ± 0.23† | 1.59 ± 0.21*† | 3.41 ± 0.90†§ | 3.39 ± 0.67†§ |
| Triglyceride (mg/dL) | 56.99 ± 8.72 | 84.37 ± 5.50* | 121.11 ± 11.21 | 199.58 ± 19.92* | 123.65 ± 12.68† | 78.21 ± 5.12*†‡ | 123.50 ± 9.53†§ | 122.92 ± 12.69†§ |
| Total cholesterol (mg/dL) | 74.15 ± 5.52 | 98.78 ± 4.65* | 98.52 ± 8.52 | 132.4 ± 9.03* | 99.43 ± 806† | 98.00 ± 4.80† | 96.61 ± 8.95† | 98.06 ± 8.74† |
| HDL (mg/dL) | 29.64 ± 1.29 | 22.40 ± 0.98* | 33.41 ± 1.40 | 23.98 ± 2.27* | 34.57 ± 1.97† | 34.07 ± 2.64† | 33.90 ± 2.60† | 34.12 ± 2.65† |
| Calculated LDL (mg/dL) | 29.68 ± 3.58 | 53.90 ± 3.56* | 46.49 ± 8.89 | 73.90 ± 3.53* | 46.58 ± 7.30† | 45.69 ± 1.36† | 43.03 ± 7.89† | 41.45 ± 9.03† |
Data are reported as mean ± SEM
*p < 0.05 when compared to ND, †p < 0.05 when compared to PDM, ‡p < 0.05 when compared to PDMCR-SM, §p < 0.05 when compared to PDMCR-L, ‖p < 0.05 when compared to PDMEX-SM
ND: Normal diet; PDM: Prediabetes with no intervention; PDMCR-SM: Prediabetes with short-term caloric restriction followed by weight maintenance; PDMCR-L: Prediabetes with long-term caloric restriction; PDMEX-SM: Prediabetes with short-term exercise followed by weight maintenance; PDMEX-L: Prediabetes with long-term exercise