Table 3.

Comparison of diagnostic parameters for predicting risk types

Variable	ET model			DP model			MVD
	Ktrans	Vp	Kep	F	Vp	PS
AUC	0.92 (0.86–0.98)	0.71 (0.62–0.81)	0.85 (0.77–0.92)	0.91 (0.85–0.97)	0.81 (0.73–0.90)	0.77 (0.68–0.87)	0.79 (0.70–0.87)
Accuracy (%)	90	69	78	88	76	76	76
Sensitivity (%)	94	63	74	87	77	72	65
Specificity (%)	87	74	83	89	75	81	82

Data in parentheses are 95% confidence interval range

ET extended Tofts, DP distributed parameter, Ktrans transfer constant, Kep efflux rate constant, Vp blood volume, F blood flow, PS permeability surface area product, MVD microvessel density. Ktrans and Kep are in units of min⁻¹, Vp is in units of mL/100 mL, F and PS are in units of mL/min/100 mL, MVD are in units of microvessels per mm². AUC = area under the receiver operating characteristic curve