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. 2022 Mar 2:NEJMoa2119451. doi: 10.1056/NEJMoa2119451

Table 2. Vaccination Status of Persons Tested for SARS-CoV-2 in England, According to Test Positivity or Negativity and Variant.

Vaccination Status, Dose, and Interval after Vaccination Overall
(N=2,663,549)
Test-Negative Status
(N=1,572,621)
Delta Variant
(N=204,154)
Omicron Variant
(N=886,774)
number (percent)
Unvaccinated 244,716 (9.2) 107,238 (6.8) 36,369 (17.8) 101,109 (11.4)
ChAdOx1 nCoV-19
Dose 1
0–3 wk 64 (<0.1) 33 (<0.1) 8 (<0.1) 23 (<0.1)
≥4 wk 16,150 (0.6) 8,470 (0.5) 2,133 (1.0) 5,547 (0.6)
Dose 2
0 or 1 wk 406 (<0.1) 224 (<0.1) 34 (<0.1) 148 (<0.1)
2–4 wk 740 (<0.1) 476 (<0.1) 28 (<0.1) 236 (<0.1)
5–9 wk 1,484 (0.1) 894 (0.1) 85 (<0.1) 505 (0.1)
10–14 wk 2,700 (0.1) 1,659 (0.1) 274 (0.1) 767 (0.1)
15–19 wk 17,775 (0.7) 10,788 (0.7) 4,013 (2.0) 2,974 (0.3)
20–24 wk 120,979 (4.5) 68,757 (4.4) 29,100 (14.3) 23,122 (2.6)
≥25 wk 292,794 (11.0) 147,721 (9.4) 46,103 (22.6) 98,970 (11.2)
Booster dose
Any: 0–6 days 102,033 (3.8) 54,613 (3.5) 13,404 (6.6) 34,016 (3.8)
BNT162b2
1 wk 60,212 (2.3) 40,203 (2.6) 2,088 (1.0) 17,921 (2.0)
2–4 wk 165,248 (6.2) 114,050 (7.3) 2,029 (1.0) 49,169 (5.5)
5–9 wk 157,008 (5.9) 98,853 (6.3) 2,291 (1.1) 55,864 (6.3)
≥10 wk 34,081 (1.3) 18,168 (1.2) 343 (0.2) 15,570 (1.8)
mRNA-1273
1 wk 31,958 (1.2) 22,722 (1.4) 845 (0.4) 8,391 (0.9)
2–4 wk 76,935 (2.9) 53,353 (3.4) 417 (0.2) 23,165 (2.6)
5–9 wk 22,745 (0.9) 13,917 (0.9) 92 (<0.1) 8,736 (1.0)
≥10 wk 80 (<0.1) 38 (<0.1) 1 (<0.1) 41 (<0.1)
ChAdOx1 nCoV-19
1 wk 158 (<0.1) 107 (<0.1) 10 (<0.1) 41 (<0.1)
2–4 wk 444 (<0.1) 294 (<0.1) 19 (<0.1) 131 (<0.1)
5–9 wk 440 (<0.1) 264 (<0.1) 12 (<0.1) 164 (<0.1)
≥10 wk 84 (<0.1) 48 (<0.1) 0 36 (<0.1)
BNT162b2
Dose 1
0–3 wk 12,530 (0.5) 7,038 (0.4) 944 (0.5) 4,548 (0.5)
≥4 wk 54,183 (2.0) 29,759 (1.9) 5,381 (2.6) 19,043 (2.1)
Dose 2
0 or 1 wk 9,001 (0.3) 5,900 (0.4) 466 (0.2) 2,635 (0.3)
2–4 wk 13,125 (0.5) 9,516 (0.6) 240 (0.1) 3,369 (0.4)
5–9 wk 29,912 (1.1) 20,163 (1.3) 981 (0.5) 8,768 (1.0)
10–14 wk 91,754 (3.4) 61,014 (3.9) 5,562 (2.7) 25,178 (2.8)
15–19 wk 243,470 (9.1) 144,172 (9.2) 17,077 (8.4) 82,221 (9.3)
20–24 wk 138,085 (5.2) 72,018 (4.6) 10,348 (5.1) 55,719 (6.3)
≥25 wk 94,139 (3.5) 51,625 (3.3) 8,531 (4.2) 33,983 (3.8)
Booster dose
Any: 0–6 days 80,592 (3.0) 44,166 (2.8) 3,212 (1.6) 33,214 (3.7)
BNT162b2
1 wk 44,705 (1.7) 29,459 (1.9) 631 (0.3) 14,615 (1.6)
2–4 wk 87,980 (3.3) 64,874 (4.1) 1,220 (0.6) 21,886 (2.5)
5–9 wk 156,929 (5.9) 110,306 (7.0) 3,769 (1.8) 42,854 (4.8)
≥10 wk 104,325 (3.9) 61,534 (3.9) 1,222 (0.6) 41,569 (4.7)
mRNA-1273
1 wk 18,221 (0.7) 12,718 (0.8) 195 (0.1) 5,308 (0.6)
2–4 wk 27,480 (1.0) 20,045 (1.3) 147 (0.1) 7,288 (0.8)
5–9 wk 8,158 (0.3) 5,311 (0.3) 40 (<0.1) 2,807 (0.3)
≥10 wk 87 (<0.1) 53 (<0.1) 1 (<0.1) 33 (<0.1)
mRNA-1273
Dose 1
0–3 wk 2,544 (0.1) 1,429 (0.1) 134 (0.1) 981 (0.1)
≥4 wk 5,656 (0.2) 3,122 (0.2) 448 (0.2) 2,086 (0.2)
Dose 2
0 or 1 wk 682 (<0.1) 467 (<0.1) 35 (<0.1) 180 (<0.1)
2–4 wk 1,104 (<0.1) 855 (0.1) 13 (<0.1) 236 (<0.1)
5–9 wk 3,150 (0.1) 2,286 (0.1) 73 (<0.1) 791 (0.1)
10–14 wk 14,324 (0.5) 9,822 (0.6) 674 (0.3) 3,828 (0.4)
15–19 wk 32,913 (1.2) 20,017 (1.3) 1,627 (0.8) 11,269 (1.3)
20–24 wk 16,291 (0.6) 8,961 (0.6) 1,224 (0.6) 6,106 (0.7)
≥25 wk 1,221 (<0.1) 474 (<0.1) 16 (<0.1) 731 (0.1)
Booster dose
Any: 0–6 days 8,787 (0.3) 4,745 (0.3) 203 (0.1) 3,839 (0.4)
BNT162b2
1 wk 3,439 (0.1) 2,031 (0.1) 15 (<0.1) 1,393 (0.2)
2–4 wk 3,410 (0.1) 2,063 (0.1) 8 (<0.1) 1,339 (0.2)
5–9 wk 36 (<0.1) 20 (<0.1) 0 16 (<0.1)
≥10 wk 3 (<0.1) 0 0 3 (<0.1)
mRNA-1273
1 wk 3,001 (0.1) 1,851 (0.1) 14 (<0.1) 1,136 (0.1)
2–4 wk 3,067 (0.1) 1,913 (0.1) 5 (<0.1) 1,149 (0.1)
5–9 wk 11 (<0.1) 4 (<0.1) 0 7 (<0.1)