Fig. 5.

Anti-SARS-CoV-2 s-RBD antibody titers evaluated in COVID-19-recovered patients who did or did not receive mycophenolate mofetil.

Anti-SARS-CoV-2 s-RBD antibody titers evaluated in COVID-19-recovered (n = 12) patients before and after 3 weeks (19 days) of the first dose of Pfizer-BioNTech® BNT162b2 vaccine, as well as after 1 month (31±2 days), 4 months (125±5 days), and 6 months (165±4 days) following the second vaccine dose. Patients were divided with regard to adopting immunosuppressive treatment, including (light blue circles) or excluding (white circles) mycophenolate mofetil. Positive responders to vaccination were defined as those having reached an antibody titer ≥0.8 U/ml. Medians of antibody titers are reported for each time point, and the statistical analysis was performed by means of a non-parametric rank-sum (Mann-Whitney) test.