Table 5.
Hypertension-mediated organ damage by BP phenotype defined by 24-hr ABPM
| Normotension (n=90) |
Masked HTN (n=204) |
p-value (Masked HTN vs. normotension) |
Sustained HTN (n=109) |
p-value (Sustained HTN vs. normotension) |
p-value between 3 categories |
|
|---|---|---|---|---|---|---|
| Blood pressure | ||||||
| 24 hr ambulatory systolic BP (mmHg) | 122.6 (5.1) | 140.6 (10.9) | <0.001 | 146.8 (12.8) | <0.001 | <0.001 |
| LV structure | ||||||
| LV mass index | 32.7 (8.3) | 33.9 (7.3) | 0.219 | 34.7 (7.3) | 0.084 | 0.058 |
| LV relative wall thickness | 0.36 (0.06) | 0.36 (0.06) | 0.846 | 0.37 (0.06) | 0.329 | 0.693 |
| LV diastolic function | ||||||
| e’ (cm/s) | 8.8 (2.6) | 8.5 (2.2) | 0.488 | 7.6 (1.7) | <0.001 | <0.001 |
| E/e’ | 9.1 (2.6) | 9.1 (2.2) | 0.986 | 9.9 (2.4) | 0.026 | 0.010 |
| Albuminuria | ||||||
| Albumin/creatinine ratio | 0 (0-204) | 0 (0-727) | 0.078 | 0 (0-925) | 0.005 | 0.442 |
| Detectable albumin (%) | 16 | 26 | 0.055 | 34 | 0.004 | 0.010 |
| Coronary calcium | ||||||
| Agatston score | 0 (0-631) | 0 (0-5985) | 0.353 | 0 (0-867) | 0.09 | 0.621 |
| Presence of calcium (%) | 22 | 26 | 0.617 | 32 | 0.206 | 0.841 |
†
adjusted by race, age, gender, and body mass index
ABPM = ambulatory blood pressure monitoring; BP = blood pressure; LV = left ventricular