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. 2022 Feb 24;10:816209. doi: 10.3389/fbioe.2022.816209

FIGURE 5.

FIGURE 5

SMSC-212-5p-Exos attenuated IL-1β induced chondrocyte degeneration. IL-1β induced chondrocytes were treated with SMSC-Exos or SMSC-212-5p-Exos for 48 h qRT-PCR was utilized to analyze the mRNA expressions of Collagen II (A), Aggrecan (B) and Sox9 (C). n = 3 for each group. ##p < 0.01, ###p < 0.001 compared to NC. @p < 0.05, @@p < 0.01 compared to IL-1β. &p < 0.05 compared to IL-1β+Exo. One-way ANOVA followed Dunn’s multiple comparisons test.