TABLE 2.
Colony counts after exposure of a multidrug-resistant wild strain of M. tuberculosis to NO for periods of 3, 6, 12, 24, and 48 h
| NO (concn) | Colony count (mean ± SE) at the following exposure timesa:
|
||||
|---|---|---|---|---|---|
| 3 | 6 | 12 | 24 | 48 | |
| 70 | 113 ± 2 (4) | 75 ± 4 (4) | 85 ± 10 (4) | 66 ± 4 (4) | ND |
| 50 ± 25 (4) | 10 ± 5 (4) | ND | |||
| 90 | 97 ± 11 (2) | 91 ± 11 (2) | 71 ± 8 (2) | 36 ± 10 (2) | ND |
| 59 ± 4 (4) | 32 ± 3 (4) | 0 ± 0 (4) | |||
| 79 ± 5 (4)b | 20 ± 3 (4)b | 0 ± 0 (4)b | |||
a
Colony counts are expressed as a percentage of the count for the control. Each series represents an individual experiment; values in parentheses refer to the number of plates prepared for each experiment at each time interval. ND, not determined.
b
Results for the H37RV laboratory strain.