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Frequency of PIK3CA mutations in HNSCC with and without HPV DNA and p16INK4a overexpression (n = 89; p16 missing data n = 6).
| HNSCC | PIK3CA Gene | ||
|---|---|---|---|
| WT n (%) |
MUT n (%) |
||
| HPV (+) | p16(+) | 22 (68.8%) | 10 (31.3%) |
| p16(−) | 17 (56.7%) | 13 (43.3%) | |
| HPV (−) | p16(+) | 3 (75%) | 1 (25%) |
| p16(−) | 12 (52.2%) | 11 (47.8%) | |
