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Classification of PIK3CA gene mutations (substitutions H1047L and E542K, E545K, and E545D).
| HPV Status | PIK3CA Gene MUT | ||||||
|---|---|---|---|---|---|---|---|
| One Substitution | Two Substitutions | ||||||
| E545D % (n) |
E545K % (n) |
E542K % (n) |
H1047R % (n) |
E545D|E545K % (n) |
E545D|E542K % (n) |
E545D|H1047R % (n) |
|
| HPV (+) | 76% (19) | 8% (2) | 4% (1) | 4% (1) | 8% (2) | ND | ND |
| HPV (−) | 67% (8) | ND | ND | ND | 8% (1) | 17% (2) | 8% (1) |
| Total | 73% (27) | 5% (2) | 3% (1) | 3% (1) | 8% (3) | 5% (2) | 3% (1) |
Legend: ND = not detected.
